Marjorie Oleksiak

evolutionary genomics, population responses to environmental stressors, molecular mechanisms of adaptation

Refereed book chapters:

Oleksiak, M. F. Toxicogenomics in Biochemical Toxicology, in press.

Oleksiak, M. F. and D. L. Crawford.  Functional Genomics in Fishes: Insights into Physiological Complexity, in The Physiology of Fishes, CRC Press, 523-549, 2006.

Juried or refereed journal articles:

Williams, M. A. and M. F. Oleksiak. Signatures of Selection in Natural Populations Adapted to Chronic Pollution.  Molecular Ecology, in review.

Crawford, D. L. and M. F. Oleksiak. The biological importance of measuring individual variation.  J Exp Biol. 2007 May 1;210(Pt 9):1613-21.

Fisher, M. A. and M. F. Oleksiak. Convergence and divergence in gene expression among natural populations exposed to pollution.  BMC Genomics, Apr 25;8:108, 2007.

Oleksiak, M. F., Roach, J. L., and D. L. Crawford.  Natural variation in cardiac metabolism and gene expression in Fundulus heteroclitus.  Nature Genetics, Jan;37(1):67-72, 2005.

Adams, S. M., Oleksiak, M. F., and D. D. Duvernell.  A Set of Microsatellite Primers for the Atlantic Coastal Killifish, Fundulus heteroclitus, with applicability to related Fundulus species.  Molecular Ecology Notes (2005) 5,  275-277.

Paschall, J. E., Oleksiak, M. F., VanWye, J. D., Roach, J. L., Whitehead, J. A., Wyckoff, G., Kolell, K. J., and D. L. Crawford.  Systems level functional annotation for the analysis of gene expression.  BMC Genomics, Dec 20;5(1):96, 2004.

Oleksiak, M. F., Wu, S., Parker, C., Qu, W., Cox, R., Zeldin, D. C., and J. J. Stegeman.  Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase.  Arch. Biochem. Biophys.  Mar 15; 411(2):223-34, 2003.

Oleksiak, M. F. and D. L. Crawford.  5' Genomic Structure of Human Sp3.  Mol Biol Evol. 2002 Nov;19(11):2026-9.

Oleksiak, M. F., Churchill, G. A. and D. L. Crawford.  Variation in gene expression within and among natural populations. Nature Genetics, 32(1), 2002.

Oleksiak, M. F., Kolell, K. J., C. Javillonar and D. L. Crawford.  The Utility of Natural Populations for Microarray Analyses; Isolation of Genes Necessary for Functional Genomic Studies. Marine Biotechnology, 2001 3: S203-S211.

Oleksiak, M. F., Wu, S., Parker, C., Karchner, S. I., Stegeman, J. J., and D. C. Zeldin.  Identification, functional characterization and regulation of a new cytochrome P450 subfamily, the CYP2Ns.  J. Biol. Chem. 275(4): 2312-2321, 2000.

Oleksiak, Marjorie F., Wu, Shu, Zeldin, Darryl C., Stegman, John J.  Characterization of members of the novel cytochrome P450 subfamilies CYP2N and CYP2P from the fish Fundulus heteroclitus. Marine Environmental Research, 46(1-5): p. 125-126, 1998.

Stegeman, J. J., B. R. Woodin, H. Sing, M. F. Oleksiak, and M. Celander.  Cytochromes P450 (CYP) in tropical fishes: Catalytic activities, expression of multiple CYP proteins and high levels of microsomal P450 in liver of fishes from Bermuda.  Comp. Biochem. Physiol.  116C: 61-75, 1997.

Oleksiak, M.F. and J.J. Stegeman.  Cloning and partial sequence analysis of multiple P450 genes from the marine fish, Fundulus heteroclitus.  Marine Environmental Research, 42(1-4): p. 25, 1996.

Morrison, H., M. Oleksiak, N. Cornell, M. Sogin, and J. Stegeman.  Identification of cytochrome P4501A genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes.  Biochem. J.  308:  97-104, 1995.

Morrison, H., Oleksiak, M., Sogin, M., Stegeman, J.  Cloning and sequencing of cytochrome P4501A1 from liver of the toadfish (Opsanus tau). FASEB Journal, 1994. 8(7).

Stegeman, J., Oleksiak, M., Woodin, B., Dimare, C.  Cytochrome P450 in Antarctic fish: Environmental induction and properties of the (Dioxin-inducible) CYP1A and constitutive expression of CYP3A proteins. American Zoologist, 34(5), 1994.

Eller, M. S., Oleksiak, M. F., McQuaid, T. J. ,McAfee, S. G., Gilchrest, B. A.  The molecular cloning and expression of two CRABP cDNAs from human skin.  Experimental Cell Research, 1992. 198(2): p. 328-336, 1992.

Eller, M., Oleksiak, M., McQuaid, T., Gilchrest, B. A.  The molecular cloning of a human cellular retinoic acid-binding protein complementary DNA sequence analysis and expression in human skin cells. Clinical Research, 1991. 39(2), 1991.

Yaar, M., Eller, M., Oleksiak, M., McQuaid, T., Gilchrest, B. A. Cloning and expression of a novel nerve growth factor related molecule in human skin. Clinical Research, 39(2), 1991.