My laboratory is devoted to studies of comparative physiology of single cells from the nervous systems of fish and invertebrates. In particular, I study the role of ion channels on cell membranes in cellular communication. The molecules that compose these ion channels are remarkably similar in eukaryotes, but they are combined in different ways to accomplish their function within the design of each animal's nervous system. Marine animals historically have served as good models of mammalian physiology in this regard. Although their nervous systems are less complex than those of higher vertebrates, this relative simplicity becomes an advantage when the aim is to elucidate basic mechanisms of nervous system function.
L. A. Fieber, S. L. Carlson, T. R. Capo and M. C. Schmale. 2010.
Changes in D-Aspartate ion currents in the Aplysia nervous
system with aging. Brain Research 1343:28-36.
H. Mao, L. A. Fieber and R. E. Gawley. 2010. Novel modulator
of NaV1.1 and NaV1.2 Na+ channels in neuronal rat cells. ACS
Medic. Chem. Lett. 1:135-138.
A. R. Hasan, L. Hu, H. M. Solo-Gabriele, L. Fieber, and Y. Cai.
2010. Field-scale leaching of arsenic chromium and copper from
weathered treated wood. Environ. Pollut. 158:1479â€“1486.
L. Hu, C. Diez-Rivas, H. Solo-Gabriele, L. Fieber, A. R. Hasan,
and Y. Cai. 2010. Transport and interaction of arsenic, chromium,
and copper associated with CCA-treated wood in columns of sand
amended with peat. Chemosphere 78:989â€“995.
J. A. Litz, L. P. Garrison, L. A. Fieber, A. Martinez, J. P.
Contillo and J. R. Kucklick. 2007. Fine-scale spatial variation
of persistent organic pollutants in bottlenose dolphins (Tursiops
truncatus) in Biscayne Bay, Florida. Environ. Sci. Technol.
Gerdes, R., and Fieber, L. A. 2006. Life history and aging of
captive-reared California sea hares (Aplysia californica).
J. Amer. Assn. Lab. An. Sci. 45:40-47.
Stommes, D., L A. Fieber, C. Beno, R. Gerdes, and T. R.
Capo. 2005. Temperature effects on growth, maturation and
lifespan of the California sea hare. J. Amer. Assn. Lab. An.