2005 Winner: Rod W. Wilson
Dr. Rod W. Wilson, School of Biological and Chemical Sciences, Hatherly Laboratories, University of Exeter, Devon, UK.
Dr. Wilson’s research focuses upon the mechanisms by which
animals respond to environmental change (natural and anthropogenic)
to maintain homeostasis (internal stability) - in particular
regarding ion, water and acid-base balance, respiratory gas
exchange and nitrogenous waste excretion. Furthermore, how
these mechanisms are integrated with each other and with
behavior to provide appropriate responses to environmental
stimuli. He has used a variety of model organisms from aquatic
invertebrates and fish, to mammals. This research embraces
techniques ranging from molecular genetics to in vivo physiology
and the behavior of fish in the laboratory and in the wild.
This multi-disciplinary emphasis aims to provide a more holistic
appreciation of the homeostatic responses in complex multicellular
organisms.
Of particular relevance to RSMAS is his recent research on the
physiology of water balance in marine bony fish, animals that
are continually faced with the threat of dehydration living
in an environment that is 3 times saltier than their own body
fluids. A fascinating spin-off from this fundamental research
is the realization that the production of carbonate crystals
appears to occur in all marine bony fish. On a global scale
this has been estimated to make a significant contribution to
the marine-atmospheric carbon cycle, as the excreted calcium
carbonate (which originates from the fishes own CO2 is dense
and sinks to the sea floor, effectively removing CO2 from the
cycle as it becomes trapped in deep ocean sediments.
Dr. Wilson is therefore linking with marine biogeochemists and fish population modelers in the UK and USA to help improve these models and perhaps ultimately our predictions of global climate change. He is also engaged in molecular research into novel genes (e.g. calcium-sensing receptors) that help these fish produce the life-preserving carbonate crystals, but which may also provide information that is relevant to biomedical research, such as parathyroid disorders where calcium-sensing receptors are under active.

