| Martin Grosell
NIEHS-MFBSC Fax: 305-361-4600 Web Site http://www.rsmas.miami.edu/divs/mbf/people/mgrosell.html Email:mgrosell@rsmas.miami.edu |
M.Sc. (1993) The August Krogh Institute, University of Copenhagen, Denmark
Ph.D. (1997) The August Krogh Institute, University of Copenhagen, Denmark
PDF (1998) Biology, Odense University, Denmark
PDF (1999-02) Biology, McMaster University, Ontario, Canada
1999 SETAC/Taylor-Francis Advanced Training Fellowship
2001 Society of Experimental Biology Presidents Medal
2001 Skou Stipend, Danish National Research Foundation
Two interlinked research areas are pursued in my laboratory focusing on freshwater and marine fish and invertebrates:
(1) Physiology of metal homeostasis and toxicity in different aquatic environments.
(2) Physiology of hydromineral balance in freshwater, brackish water and marine environments.
Homeostasis of essential and non-essential metals in fish and invertebrates are in focus in my laboratory. We study mechanisms of metal uptake, metabolism and excretion as well as the toxic response resulting from elevated environmental metal concentrations. The metals currently being studied included copper, silver and lead.
Fish and invertebrates are able to osmoregulate in environmental ranging from very dilute freshwater to highly saline seawater and offer a range of organs specialized in maintaining extreme ionic gradients. While detailed studies of the special epithelial traits involved in these functions is important to understand how these animals interact with their environment, they may also offer valuable information about specialized human epithelia like the exocrine pancreas, the human colon and the renal tubules.
Grosell, M., Wood, C.M. & Walsh, P.J. (2003): Copper homeostasis and toxicity in the elasmobranch Raja erinacea and the teleost Myoxcephalus octodecemspinosus during exposure to elevated water-borne copper. Comp.Biochem.Physiol. C. 135 (2), 179-190.
Chowdhury, M.J., Grosell,. M., McDonald, D.G., & Wood, C.M. (2003): Plasma clearance of cadmium and zinc in non-acclimated and metal-acclimated trout. Aquatic Toxicology. 64, 259-275.
Hogstrand, C., Grosell, M., Wood, C.M. & Hansen, H.J.M. (2003): Internal redistribution of radiolabelled silver among tissues of rainbow trout (Oncorhynchus mykiss) and European eel (Anguilla anguilla): the influence of silver speciation. Aquat.Toxicol. 63, 139-157.
McDonald, M.D., Wood, C.M., Grosell, M. & Walsh, P.J. (2003): The branchial and renal handling of urea in the gulf toadfish, Opsanus beta: the effect of exogenous urea loading. Comp.Biochem.Physiol. 134A: 763-776.
Bury, N. & Grosell, M. (2003): Iron acquisition by teleost fish.
Comp.Biochem.Physiol. C 135, 97-105.