Kathleen Rein
Center Investigator
Department of Chemistry
Florida International University
University Park
Miami, Florida 3319
Phone: 305-348-6682 Fax: 305-3772
Website: www.rsmas.miami.edu/groups/niehs/arch
Email: reink@fiu.edu
Biography
Education
| B.Sc. | (1981) | Chemistry, University of Central Florida |
| M. Sc. | (1983) | Industrial Chemistry, University of Central Florida |
| Ph. D. | (1991) | Organic Chemistry, University of Miami |
| Post Doc. | (1992-1994) | University of Maimi, Rosensteil School |
Research Interests
Isolation and identification of secondary metabolites from marine microalgae.
These include primarily cyanobacteria from both marine and freshwater
environments and dinoflagellates from marine environments. Many of these
compounds are toxic and human exposures represent a threat to public health.
In addition, we are studying the biosynthesis of polyketide toxins at
the genomic level. Synthesis of analogs of marine toxins.
Recent Publication
Purkerson-Parker, S. L.; Fieber, L. A.; Rein, K. S.; Podona, T.; Baden, D. G.; (2000) “Brevetoxin Derivatives that Inhibit Toxin Activity”. Chem. Biol., 7, 385 – 393.
Berry, J. P.; Reece, K. S.; Rein, K. S.; Baden, D. G.; Haas, L. W.; Ribeiro,
W. L.; Shields, J. D.; Snyder, R. V.; Vogelbein, W. K.; Gawley, R. E.
(2002) “ Are pfiesteria species toxicogenic? Evidence against
production of ichthyotoxins by pfiesteria shumwayae.” PNAS, 99 (17), 10970-10975.
> Snyder, R. V., Gibbs, P. D. L., Palacios, A., Abiy, L., Dickey, R.,Lopez, J. V., Rein, K. S., (2003) “Polyketide Synthase Genes from Marine Dinoflagellates”. Mar. Biotech. 5 (1), 1-12.
Carcache, L. M.; Rodriguez, J.; Rein, K. S., (2003) “The Structural Basis for Kainoid Selectivity at AMPA Receptors Revealed by Low-Mode Docking Calculations” Bioorg. Med. Chem. 11, 551-559.