Department of Chemistry
University of Miami
P.O. Box 249118
Coral Gables,
Florida 33124-0431
Phone: 305-284-3279
Fax:305-668-3313
Web Site http://www.as.miami.edu/rgawley/
Email:rgawley@miami.edu
Biography
Education
| B. S. | (1970) | Chemistry, Stetson University, Deland Florida | |
| Ph.D. | (1975) | Organic Chemistry, Duke University, Durham, North Carolina | |
| Research Associate | (1975-77) | Peptide Chemistry University of North Carolina, Chapel Hill |
Research Interests
My group has two broad focus areas: synthetic and mechanistic organic chemistry, and chemical aspects of marine toxins, including SAR, sensing, and chemical modification through semisynthesis. In the area of marine toxins, we have a long-standing collaboration with scientists with the University of Miami's Marine and Freshwater Biomedical Sciences Center to study the chemistry and pharmacology of substances such as brevetoxin, ciguatoxin, and saxitoxin. Currently, we are focusing on the following projects:
- Develop fluorescent sensors for marine toxins using molecular recognition concepts and combinatorial chemistry
- Isolate, purify, and characterize new cyanobacteria
Recent Publications
D. G. Baden; K. S. Rein; R. E .Gawley; G. Jeglitsch; D. J. Adams “Marine Toxins: Scientific Approaches, Synthetic Transformations, and Molecular Mechanisms” in Harmful and Toxic Algal Blooms, T. Yasumoto; Y. Oshima; Y. Fukuyo, Eds., Intergovernmental Oceanographic Commission of UNESCO, 1996, pp. 473-476.
D. G. Baden; K. S. Rein;R.E. Gawley “Marine Toxins: How They are Studied and What They Can Tell Us in: Molecular Approaches to the Study of the Oceans, K. Cooksey, ed., Chapman and Hall: London, 1998, pp. 487-514.
R. E. Gawley, Q. Zhang, P. I. Higgs, S. Wang, R. M. Leblanc, “Anthracylmethyl Crown Ethers as Fluorescence Sensors of Saxitoxin” Tetrahedron Lett., 1999, 40, 5461-5465, corrigendum 6135.
S. Wang; P. K. Datta; Q. Zhang;R. E. Gawley; R. M. Leblanc “Amphiphilic Anthracyl Crown Ether: A Langmuir and Langmuir-Blodgett Film Study” Langmuir, 2000, 16, 4607-4612.