The export of biogenic carbon to the seafloor was computed from primary productivity in the Intra-Americas Sea to evaluate the potential availability of organic matter to the benthos. A model to predict standing stock of macrobenthic infauna based on offshore phytoplankton biomass and pigment concentration was derived. Available primary productivity, pigments in the surface, carbon flux values obtained from sediment traps and estimated from sediment cores were used to emulate the potential fluxes to bottom. The primary productivity in the IAS region shows a large variability, the values range from 104 to >1000 mgCm-2d-1. The highest values were related to eddy circulation and fronts (Venezuela Basin), upwelling locations (off Colombia, Margarita, the Cariaco Basin and the Yucatan Straits) and areas influenced by river outflow (regions of the Gulf of Mexico). The percentage of carbon calculated to reach the bottom constitutes 1.2 to 8.8% of the primary production influenced by hydrodynamics. The distribution of organic matter in the sediments ranges from 37.5 to 1315 gCm-2, it follows a consistent pattern with primary production. The respond to the biogenic carbon export to the sea floor shows in the macrobenthic standing stock a normal distribution, low benthic standing stock is found related to most oligotrophic areas, absence of macrobenthic standing stock is found asociated to fronts and upwellings.